Widespread Over-Expression of the X Chromosome in Sterile F1 Hybrid Mice
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چکیده
منابع مشابه
Widespread Over-Expression of the X Chromosome in Sterile F1 Hybrid Mice
The X chromosome often plays a central role in hybrid male sterility between species, but it is unclear if this reflects underlying regulatory incompatibilities. Here we combine phenotypic data with genome-wide expression data to directly associate aberrant expression patterns with hybrid male sterility between two species of mice. We used a reciprocal cross in which F₁ males are sterile in one...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2010
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1001148